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Ubiad1 +/+ control mice by monitoring tumor growth kinetics after the tumors had reached a palpable size (Fig

Cell culture Human lung carcinoma A549 cells, mouse fibroblasts 3T3-L1, human lung adenocarcinoma cell line NCl-H441 (ATCC, LGC Standards S.a.r.l, Molsheim, France) and 13s24 rat olfactory neuroblasts (Coronas et al, 1997) were grown in Dulbeccos Modified Eagles Medium with low glucose (1 g/L) containing 10% fetal calf serum (DMEM 10% FCS, PAA Laboratories, Canada), streptomycin plus penicillin (100 units/mL

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[16] [17] In obesity trials (SURMOUNT program), higher doses produced weight loss averaging 15-20% of body weight, while diabetes trials (SURPASS program) showed more modest but still significant weight reductions

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